Colic is a surname. Notable people with the surname include:

• Elvir Colic (born 1986), Bosnian footballer
• Ljiljana Colic (born 1956), politician from Serbia
• Mladen Colic (born 1982), Serbian pianist
• Ratko Colic (1918-1999), Serbian footballer
• Tomislav Colic (born 1987), Serbian footballer
• Zdravko Colic (born 1951), singer from Bosnia and Herzegovina

Colic (from Greek κολικός kolikos, "relative to the colon") or cholic is a form of pain which starts and stops abruptly. It occurs due to muscular contractions of a hollow tube (colon, ureter, gall bladder, etc.) in attempt to relieve an obstruction by forcing content out. It may be accompanied by vomiting and sweating. Types include:

• Baby colic, a condition, usually in infants, characterized by incessant crying
• Renal colic, a pain in the flank, characteristic of kidney stones
• Biliary colic, blockage by a gallstone of the common bile duct or cystic duct
• Horse colic, a potentially fatal condition experienced by horses, caused by intestinal displacement or blockage
• Devon colic, an affliction caused by lead poisoning
• Painter's colic or lead poisoning