CLARITY is a method of making brain tissue transparent using acrylamide-based hydrogels built from within, and linked to, the tissue, and as defined in the initial paper, represents "transformation of intact biological tissue into a hybrid form in which specific components are replaced with exogenous elements that provide new accessibility or functionality". When accompanied with antibody or gene-based labeling, CLARITY enables highly detailed pictures of the protein and nucleic acid structure of organs, especially the brain. It was developed by Karl Deisseroth and his colleagues at the Stanford University School of Medicine.

Clarity may refer to:

• Clarity (Jimmy Eat World album)
• Clarity (Sifow album)
• Clarity (Zedd album)
  • "Clarity" (Zedd song), a 2012 song by Russian-German electronic dance music producer Zedd featuring the vocals of British singer Foxes
• Clarity, a 2010 album by Article One
• "Clarity" (John Mayer song), a 2003 song by John Mayer
• "Clarity" (Senakah song)
• "Clarity", an instrumental song by Linkin Park from LP Underground 12
• "The Clarity" a 2014 single by Sleep