An
antibody (Ab), also known as an
immunoglobulin (Ig), is a large, Y-shaped
protein produced mainly by
plasma cells that is used by the
immune system to identify and neutralize pathogens such as
bacteria and
viruses. The antibody recognizes a unique molecule of the harmful agent, called an
antigen, via the variable region. Each tip of the "Y" of an antibody contains a
paratope (analogous to a lock) that is specific for one particular
epitope (similarly analogous to a key) on an antigen, allowing these two structures to bind together with precision. Using this binding mechanism, an antibody can
tag a
microbe or an infected cell for attack by other parts of the immune system, or can neutralize its target directly (for example, by blocking a part of a microbe that is essential for its invasion and survival). The ability of an antibody to communicate with the other components of the immune system is mediated via its Fc region (located at the base of the "Y"), which contains a conserved
glycosylation site involved in these interactions. The production of antibodies is the main function of the
humoral immune system.