An
antitoxin is an
antibody with the ability to neutralize a specific
toxin. Antitoxins are produced by certain
animals,
plants, and
bacteria. Although they are most effective in neutralizing toxins, they can kill bacteria and other microorganisms. Antitoxins are made within organisms, but can be injected into other organisms, including humans. This procedure involves injecting an animal with a safe amount of a particular toxin. Then, the animal’s body makes the antitoxin needed to neutralize the toxin. Later, the
blood is withdrawn from the animal. When the antitoxin is obtained from the blood, it is purified and injected into a human or other animal, inducing
passive immunity. To prevent
serum sickness, it is often best to use antitoxin generated from the same species (e.g. use human antitoxin to treat humans).