Amphetamine (contracted from ) is a
potent central nervous system (CNS)
stimulant that is used in the treatment of
attention deficit hyperactivity disorder (ADHD),
narcolepsy, and
obesity. Amphetamine was discovered in 1887 and exists as two
enantiomers:
levoamphetamine and
dextroamphetamine.
Amphetamine properly refers to a specific chemical, the
racemic free base, which is equal parts of the two enantiomers, levoamphetamine and dextroamphetamine, in their pure amine forms. However, the term is frequently used informally to refer to any combination of the enantiomers, or to either of them alone. Historically, it has been used to treat nasal congestion and depression. Amphetamine is also used as a
performance and
cognitive enhancer, and recreationally as an
aphrodisiac and
euphoriant. It is a
prescription drug in many countries, and unauthorized possession and distribution of amphetamine are often tightly controlled due to the significant health risks associated with
recreational use.