MAME (an acronym of Multiple Arcade Machine Emulator) is an emulator application designed to recreate the hardware of arcade game systems in software on modern personal computers and other platforms. The intention is to preserve gaming history by preventing vintage games from being lost or forgotten. The aim of MAME is to be a reference to the inner workings of the emulated arcade machines; the ability to actually play the games is considered "a nice side effect". Joystiq has listed MAME as an application that every gamer should have.

Mame may refer to:

• Mame (musical), a 1966 Broadway musical by Jerry Herman
  • Mame (film), a 1974 American film based on the musical
  • Mame (film soundtrack), a soundtrack album
• MAME, an emulator for arcade games, which also incorporates the MESS computer and console emulator.
• Mame, a size classification of bonsai
• Mame people or Mam, an indigenous people of Mexico
• Mame Soramame, a fictional character from the anime and manga series Dr. Slump