Ithaca is an island in Greece.

Ithaka Harbors, Inc. is a nonprofit organization whose stated mission is to "help the academic community use digital technologies to preserve the scholarly record and to advance research and teaching in sustainable ways." It is the parent company of digital library website JSTOR, the digital preservation service Portico, and the research and consulting group Ithaka S+R. It was launched by the Andrew W. Mellon Foundation.