The universe of the manga Blame! created by Tsutomu Nihei is home to the following fictional characters and locations:

• Killy (霧亥 Kirii) is a main character of Blame!. He is tasked by an unknown agency with finding a human in the 32-AU radius Megastructure who still possesses the Net Terminal Gene, a genetic marker necessary for safe access to the Netsphere, from which the functions of the Megastructure may be controlled. He is equipped with a Gravitational Beam Emitter (GBE), a compact but powerful weapon capable of creating holes miles long in the Megastructure. He is soon joined by Cibo in his quest.