TRE (or Tre) may refer to:

• Tre recombinase, an experimental cure for HIV
• Thyroid hormone response element (see Hormone response element)
• Tetracycline response element, a DNA sequence important in tetracycline-controlled transcriptional activation

Tré may refer to:

• Tré Cool, drummer for the American band Green Day
• ¡Tré!, the eleventh studio album by the same band.
• Tré, Benin, a town and arrondissement in the Collines department of Benin

¡Tré! is the eleventh studio album by the American punk rock band Green Day. It is the third and final installment in the ¡Uno! ¡Dos! ¡Tré! trilogy, a series of studio albums that were released from September to December 2012. Green Day started recording material for the album on February 14, 2012, and finished on June 26, 2012. ¡Tré! follows the power pop style of ¡Uno!, and the garage rock feel of ¡Dos! The album's title is a nod to the band's drummer Tré Cool, who turned 40 years old 2 days after the release of the album.