tophus – מילון אנגלי-אנגלי
tophus
n.
abnormal mineral deposit (Medicine)
Tophus
A
tophus (Latin: "stone", plural
tophi) is a deposit of
uric acid crystals, in the form of monosodium urate crystals, in people with longstanding
hyperuricemia (high levels of uric acid in the blood). Tophi are
pathognomonic for the disease
gout. Most people with tophi have had previous attacks of acute
arthritis, eventually leading to the formation of tophi. Chronic tophaceous gout is known as
Harrison Syndrome.
tophus
Noun
1. a deposit of urates around a joint or in the external ear; diagnostic of advanced or chronic gout
(synonym) chalkstone
(hypernym) urate
2. an incrustation that forms on the teeth and gums
(synonym) tartar, calculus
(hypernym) crust, incrustation, encrustation
Tophus
(n.)
One of the mineral concretions about the joints, and in other situations, occurring chiefly in gouty persons. They consist usually of urate of sodium; when occurring in the internal organs they are also composed of phosphate of calcium.
(n.)
Calcareous tufa.
Webster's Revised Unabridged Dictionary (1913), edited by Noah Porter.
About
Tophus
A nodular mass of uric acid crystals. Tophi are characteristically deposited in different soft tissue areas of the body in gout. The word tophus comes via Latin from the Greek tophos meaning a porous volcanic stone. In chronic (tophaceous) gout, nodular masses of uric acid crystals (tophi) deposit in different soft tissue areas of the body. Even though tophi are most commonly found as hard nodules around the fingers, at the tips of the elbows, and around the big toe, tophi nodules can appear anywhere in the body. They have been reported in unexpected areas such as in the ears, vocal cords, or around the spinal cord!
