Prophase (from the
Greek πρό, "before" and φάσις, "stage"), is a stage of
mitosis in which the
chromatin condenses into double rod-shaped structures called
chromosomes in which the chromatin becomes visible. This process, called
chromatin condensation, is involved with the
condensin complex. Since the genetic material has been replicated in the prior
interphase of the
cell cycle, there are two identical copies of each chromosome in the cell. Those copies are called sister
chromatids and they are attached to each other at a
DNA element present on every chromosome called the
centromere. Also during prophase,
giemsa staining can be applied to elicit
G-banding in chromosomes.