Phosphatidylcholines (PC) are a class of
phospholipids that incorporate
choline as a headgroup. They are a major component of
biological membranes and can be easily obtained from a variety of readily available sources, such as
egg yolk or
soybeans, from which they are mechanically or chemically extracted using
hexane. They are also a member of the
lecithin group of yellow-brownish fatty substances occurring in animal and plant tissues. Dipalmitoyl phosphatidylcholine (aka: lecithin) is a major component of
pulmonary surfactant and is often used in the
L/S ratio to calculate fetal lung maturity. While phosphatidylcholines are found in all plant and animal cells, they are absent in the membranes of most bacteria, including
Escherichia coli. Purified phosphatidylcholine is produced commercially.