Off Key (also known as Desafinado) is a 2001 Spanish-British-Italian comedy film written and directed by Manuel Gómez Pereira. In it Joe Mantegna, Danny Aiello, and George Hamilton star as three celebrity tenors. Although they perform and have some good times together, they are rivals onstage and in their private lives. They also undergo intense scrutiny from the paparazzi and gossip press over their love lives and careers. The film was loosely inspired by the real life Three Tenors, Plácido Domingo, Luciano Pavarotti, and José Carreras.

Off-key is musical content that is not at the expected frequency or pitch period, either with respect to some absolute reference frequency, or in a ratiometric sense (i.e. through removal of exactly one degree of freedom, such as the frequency of a keynote), or pitch intervals not well-defined in the ratio of small whole numbers.