Peripheral neuropathy (
PN) is damage to or disease affecting
nerves, which may impair sensation, movement, gland or organ function, or other aspects of health, depending on the type of nerve affected. Common causes include systemic diseases (such as
diabetes or
leprosy),
vitamin deficiency,
medication (e.g.,
chemotherapy),
traumatic injury,
radiation therapy, excessive alcohol consumption, immune system disease, Coeliac disease, or viral infection. It can also be
genetic (present from birth) or
idiopathic (no known cause). In conventional medical
usage, the word
neuropathy (, "nervous system" and , "disease of") without modifier usually means
peripheral neuropathy.