Mydriasis is the
dilation of the
pupil, usually defined as when having a non-physiological cause, but sometimes defined as potentially being a physiological
pupillary response. Non-physiological causes of mydriasis include
disease,
trauma, or the use of
drugs. Normally, as part of the
pupillary light reflex, the pupil dilates in the
dark and
constricts in the
light to respectively improve vividity at night and to protect the
retina from sunlight damage during the day. A
mydriatic pupil will remain excessively large even in a bright environment. The excitation of the radial fibres of the iris which increases the pupillary aperture is referred to as a mydriasis. More generally, mydriasis also refers to the natural dilation of pupils, for instance in low light conditions or under sympathetic stimulation.