5a-Dihydrodeoxycorticosterone (abbreviated as DHDOC), also known as 21-hydroxy-5a-pregnan-20-one, is an endogenous progestogen and neurosteroid. It is synthesized from the adrenal hormone deoxycorticosterone (DOC) by the enzyme 5a-reductase type I. DHDOC is an agonist of the progesterone receptor, as well as a positive allosteric modulator of the GABA_A receptor, and is known to have anticonvulsant effects.

5a-Dihydrodeoxycorticosterone (abbreviated as DHDOC), also known as 21-hydroxy-5a-pregnan-20-one, is an endogenous progestogen and neurosteroid. It is synthesized from the adrenal hormone deoxycorticosterone (DOC) by the enzyme 5a-reductase type I. DHDOC is an agonist of the progesterone receptor, as well as a positive allosteric modulator of the GABA_A receptor, and is known to have anticonvulsant effects.