Chlorphenamine (
INN),
chlorpheniramine (
USAN, former
BAN) or
piriton (trade name), commonly marketed in the form of chlorphenamine
maleate (Chlorphen-12), is a
first-generation alkylamine antihistamine used in the prevention of the
symptoms of
allergic conditions such as
rhinitis and
urticaria. Its sedative effects are relatively weak compared to other first-generation antihistamines. Chlorphenamine is one of the most commonly used antihistamines in small-animal veterinary practice. Although not generally approved as an
antidepressant or
anti-anxiety medication, chlorphenamine appears to have these properties as well.
