Chemotaxis (from
chemo- +
taxis) is the movement of an organism in response to a chemical stimulus.
Somatic cells,
bacteria, and other
single-cell or
multicellular organisms direct their movements according to certain chemicals in their environment. This is important for bacteria to find food (e.g.,
glucose) by swimming toward the highest concentration of food molecules, or to flee from
poisons (e.g.,
phenol). In multicellular organisms, chemotaxis is critical to early development (e.g., movement of
sperm towards the egg during
fertilization) and subsequent phases of development (e.g., migration of
neurons or
lymphocytes) as well as in normal function. In addition, it has been recognized that mechanisms that allow chemotaxis in animals can be subverted during
cancer metastasis.