Carboplatin, or
cis-diammine(1,1-cyclobutanedicarboxylato)platinum(II) (trade names
Paraplatin and
Paraplatin-AQ) is a
chemotherapy drug used against some forms of
cancer (mainly ovarian carcinoma, lung, head and neck cancers as well as endometrial, esophageal, bladder, breast and cervical; central nervous system or germ cell tumors; osteogenic sarcoma, and as preparation for a stem cell or bone marrow transplant). It was introduced in the late 1980s and has since gained popularity in clinical treatment due to its vastly reduced side effects compared to its parent compound
cisplatin. Cisplatin and carboplatin belong to the group of
platinum-based antineoplastic agents, and interact with
DNA to interfere with
DNA repair.