BRU may stand for:

• IOC country code for Brunei
• IATA Code for Brussels Airport
• 5-Bromouracil, a brominated derivative of uracil
• Buller Rugby Football Union
• Bus Riders Union (Los Angeles), a civil rights organization in Los Angeles, California
• Bus Riders Union (Vancouver), a non-profit organization in Vancouver, British Columbia
• Biserica Româna Unita cu Roma, Greco-Catolica, the Romanian Church United with Rome, Greek-Catholic
• Begum Rokeya University, in Rangpur, Bangladesh
• Backup and Restore Utility, similar to tar (computing)

Bru may refer to:

• Bru people, an ethnic group of Laos, Vietnam, and Thailand
• Bru or Reang, a tribe from northeast India
• Saint Bru or Saint Brioc, a 5th-century Welsh holy man who became the first abbot of Saint-Brieuc in Brittany
• Bru (surname)

Brú is a farmstead and road junction in northwestern Iceland in Vestur-Húnavatnssýsla county. It is located in the Northwest Political constituency. It has a filling station and a guesthouse. It is located at the southern tip of Hrútafjörður where the river Hrútafjarðará has its estuary with the Arctic Ocean.

Brû is a commune in the Vosges department in Lorraine in northeastern France.

Brue is a village on the Isle of Lewis in the West Side district, in the Outer Hebrides, Scotland. It is a crofting township and it is composed of two areas: Am Baile Staigh, which is nearer the coast, and Pàirc Bhrù, which runs towards the moor. In total it covers a road distance of 2.5 km. Brue is situated on a minor road which joins to the A858, and is within the parish of Barvas.