An
adenoma (from
Greek αδένας, , "gland" + -ώμα, , "tumor") (; plural
adenomas or
adenomata ) is a benign
tumor of
epithelial tissue with
glandular origin, glandular characteristics, or both. Adenomas can grow from many glandular
organs, including the
adrenal glands,
pituitary gland,
thyroid,
prostate, and others. Some adenomas grow from epithelial tissue in nonglandular areas but express glandular tissue structure (as can happen in
familial polyposis coli). Although adenomas are
benign, over time they may
transform to become
malignant, at which point they are called
adenocarcinomas. Most adenomas do not transform. But even while benign, they have the potential to cause serious health complications by compressing other structures (
mass effect) and by producing large amounts of
hormones in an unregulated, non-feedback-dependent manner (causing
paraneoplastic syndromes). Some adenomas are too small to be seen macroscopically but can still cause clinical symptoms.