Samosata (Armenian: , Samósata, šmīšaṭ) was an ancient city on the right (west) bank of the Euphrates whose ruins existed at the modern city of Samsat, Adıyaman Province, Turkey until the site was flooded by the newly constructed Atatürk Dam. Even though the city had a predominantly Syriac-speaking population, Hellenistic culture played an important role there. The city is sometimes confused with Arsamosata.

Samosata (Armenian: , Samósata, šmīšaṭ) was an ancient city on the right (west) bank of the Euphrates whose ruins existed at the modern city of Samsat, Adıyaman Province, Turkey until the site was flooded by the newly constructed Atatürk Dam. Even though the city had a predominantly Syriac-speaking population, Hellenistic culture played an important role there. The city is sometimes confused with Arsamosata.