SPO may refer to:

Entertainment

• Scarborough Philharmonic Orchestra, a community orchestra performing in Scarborough, Ontario.

SPO:) is a Lithuanian monthly sports magazine owned by media conglomerate UAB MKG. SPO:) is the first and currently only magazine in Lithuania dedicated to recent developments in various sports. Its first issue was published in January 2005. SPO:) includes a large number of color photographs, scouting reports from NBA and Euroleague, and posters in the center of the magazine.

SPSS Statistics is a software package used for statistical analysis. Long produced by SPSS Inc., it was acquired by IBM in 2009. The current versions (2015) are officially named IBM SPSS Statistics. Companion products in the same family are used for survey authoring and deployment (IBM SPSS Data Collection), data mining (IBM SPSS Modeler), text analytics, and collaboration and deployment (batch and automated scoring services).

The Social Democratic Party of Austria (, SPÖ) is a social-democratic political party in Austria. The oldest extant political party in Austria, the SPÖ is a member of the Socialist International, Progressive Alliance and Party of European Socialists. Before adopting the current title in 1991, the SPÖ was named Social Democratic Workers' Party of Austria (Sozialdemokratische Arbeiterpartei Österreichs, SDAPÖ) from 1888 to 1945 and, later, Socialist Party of Austria (Sozialistische Partei Österreichs) until 1991.