Retinoblastoma – מילון אנגלי-עברי
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Retinoblastoma
Retinoblastoma (Rb) is a
rare form of
cancer that rapidly develops from the immature cells of a
retina, the light-detecting
tissue of the eye. It is the most common malignant cancer of the eye in children, and it is almost exclusively found in young children.
retinoblastoma
Noun
1. malignant ocular tumor of retinal cells; usually occurs before the third year of life; composed of primitive small round retinal cells
(hypernym) malignant tumor, malignant neoplasm, metastatic tumor
Retinoblastoma
A malignant eye tumor caused by the loss of a pair of tumor-suppressor genes. An inherited form of retinoblastoma (it typically appears at birth, leads to multiple tumors and affects both eyes) is due to a transmissible (germline) mutation followed by an acquired (somatic) mutation. The sporadic form of retinoblastoma (it has later onset and leads to a single tumor in one eye) is due to acquired (somatic) mutations of both tumor-suppressor genes. When the tumor is detected at an early stage, it can sometimes be treated locally, but it oftren unfortunately requires removal of the eye (enucleation).
retinoblastoma
An eye cancer that most often occurs in children younger than 5 years. It occurs in hereditary and nonhereditary (sporadic) forms.
