Psilotaceae is a family of fern-like plants (in order Psilotales) consisting of two genera, Psilotum and Tmesipteris. The two genera are very different and in the past Tmesipteris has been placed in its own family, Tmesipteridaceae, but most classifications continue to place it in Psilotaceae. The relationships of Psilotaceae have been unclear, in part because the plants lack roots or true leaves, but recent molecular systematic studies suggest a relationship to the fern family Ophioglossaceae.