Lansoprazole ( ;
INN) is a
proton-pump inhibitor (PPI) which inhibits the
stomach's production of
gastric acids. It is manufactured by a number of companies worldwide under several brand names. In the United States, it was first approved by the
Food and Drug Administration (FDA) in 1995. Prevacid patent protection expired on November 10, 2009. Since 2009, lansoprazole has been available over the counter (OTC) in the U.S. in a 15-mg dose marketed by
Novartis as Prevacid 24HR. In Australia, it is marketed by
Pfizer as Zoton.