Koko or
KOKO may refer to:
People, animals, and plants
- Emperor Koko (830–887), 58th emperor of Japan
- King Koko of Nembe (1853–1898)
- Koko Taylor (1928–2009), R&B singer
- Koko Pimentel (born 1964), Philippine politician
- Julio "Koko" Sosa , Argentine guitarist
- Koko Stambuk (born 1977), Chilean singer-songwriter and producer
- Koko (gorilla) (born 1971), gorilla that underwent training in Gorilla Sign Language (based on American Sign Language) and who befriended a kitten
- Koko, lead guitarist of the Indian rock band Agnee
- A local name for the Lebbek Tree, Albizia lebbeck
- Ko'ko' a local name for the Guam rail
- Koko (dog), the Australian kelpie dog featured in the 2011 film Red Dog
- Ko-ko, a title in the Manchu language and the Chinese language