Khan or KHAN may refer to:

• Genghis Khan
• Khagan, the royal title of the ruler of the Mongol Empire
• Khan (title), a title for a ruler in Turkic and Mongolian languages and used by various ethnicities
• Khan (surname), a family name
• a caravanserai (roadside inn for caravans)
• Khan River, an ephemeral river in Namibia
• Administrative divisions of Cambodia
• Khan Academy, a non-for-profit educational organization
• State Oil Co. v. Khan, a 1997 U.S. Supreme Court decision in antitrust law, often referred to just as Khan.

Khan, Kahn (; ; Azerbaijani: xan; Ottoman: han; Old Turkic: , kaɣan; Chinese: 可汗, kèhán; Goguryeo : 皆, key; Silla: 干, kan; Baekje: 瑕, ke; Manchu: , Pashto: خان , Balochi: خان Hindi: ख़ान; Nepali: खाँ Bengali: খ়ান; Bulgarian: хан, Chuvash: хун, hun) is originally a title for a sovereign or a military ruler, widely used by medieval nomadic Mongolic and Turkic tribes living to the north of China. "Khan" also occurs as a title in the Xianbei confederation for their chief between 283 and 289. The Rourans were the first people who used the titles khagan and khan for their emperors, replacing the Chanyu of the Xiongnu, whom Grousset and others assume to be Turkic. Subsequently the Ashina adopted the title before the Mongols brought it to the rest of Asia. In the middle of the sixth century the Iranians knew of a "Kagan – King of the Turks".

Khan! is an American television detective series. Set in San Francisco, it is named after the central character, a Chinese-American detective, played by Khigh Dhiegh. Evan C. Kim and Irene Yah-Ling Sun are featured as his relatives. Four episodes were aired in February 1975 on CBS. Dhiegh is best known for his portrayal of the Chinese spy Wo Fat on Hawaii Five-O from 1968 to 1980.