Interstitial fluid or
tissue fluid is a solution that bathes and surrounds the tissue cells of multicellular animals. It is the main component of the
extracellular fluid, which also includes
plasma and
transcellular fluid. The interstitial fluid is found in the interstices - the spaces between cells (also known as the tissue spaces). On average, a person has about 10 litres (2.4 imperial gallons or ~2.9 US gal) of interstitial fluid (they make up 16% of the total body weight), providing the cells of the body with nutrients and a means of waste removal.