In chemistry, a hydride is the anion of hydrogen, H^-, or, more commonly, it is a compound in which one or more hydrogen centres have nucleophilic, reducing, or basic properties. In compounds that are regarded as hydrides, the hydrogen atom is bonded to a more electropositive element or group. Compounds containing hydrogen bonded to metals or metalloid may also be referred to as hydrides, even though in this case the hydrogen atoms can have a protic character. Almost all of the elements form binary compounds with hydrogen, the exceptions being He, Ne, Ar, Kr, Pm, Os, Ir, Rn, Fr, and Ra.