Hélio may refer to:

• Hélio Gracie (1913–2009), a founder of Brazilian Jiu-Jitsu
• Hélio Castroneves (born 1975), Brazilian auto racing driver
• Hélio (footballer) (born 1986), Brazil-born Hong Kong footballer

Helios is the personification of the sun in Greek mythology. It may also refer to:

• Helio (comics), a character in the Marvel Comics universe
• Helios, a character in Helios Eclipse drawn by Kaoru and serialized in Gempak
• Helios, a character in the anime Sailor Moon
• Helios, the name of a Bakugan in the Bakugan Battle Brawlers series
• Victor Helios, an alias for Victor Frankenstein, a character from the Dean Koontz's Frankenstein series