A
fasciculation , or
muscle twitch, is a small, local, involuntary
muscle contraction and relaxation which may be visible under the skin. Deeper areas can be detected by
EMG testing, though they can happen in any skeletal muscle in the body. Fasciculations arise as a result of
spontaneous depolarization of a
lower motor neuron leading to the synchronous contraction of all the
skeletal muscle fibers within a single motor unit. An example of normal spontaneous depolarization is the constant contractions of
cardiac muscle, causing the
heart to beat. Usually, intentional movement of the involved muscle causes fasciculations to cease immediately, but they may return once the muscle is at rest again.