Eresos-Antissa is a former municipality on the island of Lesbos, North Aegean, Greece. Since the 2011 local government reform it is part of the municipality Lesbos, of which it is a municipal unit. It is located in the westernmost part of the island, and is the largest municipal unit of the island in land area at 290.947 km². Its population was 5,530 at the 2001 census. The seat of the municipality was in Eresos (pop. 1,097). The next largest towns are Ántissa (900), Mesótopos (853), Vatoússa (529) and Chidira (488).

Eresos-Antissa is a former municipality on the island of Lesbos, North Aegean, Greece. Since the 2011 local government reform it is part of the municipality Lesbos, of which it is a municipal unit. It is located in the westernmost part of the island, and is the largest municipal unit of the island in land area at 290.947 km². Its population was 5,530 at the 2001 census. The seat of the municipality was in Eresos (pop. 1,097). The next largest towns are Ántissa (900), Mesótopos (853), Vatoússa (529) and Chidira (488).