Epica or EPICA may refer to:

• Epica (band), a Dutch symphonic metal band
• Epica (album), an album by the power metal band Kamelot
• The European Project for Ice Coring in Antarctica (EPICA)
• The Epica Awards (International Advertising Awards)
• Epica (RAID series), a series of storage arrays developed by Proware Technology Corporation
• Daewoo Tosca, also known as Chevrolet Epica or Holden Epica
• Daewoo Magnus, also known as Chevrolet Epica
• Banksia epica, a South Australian native bush

The European Project for Ice Coring in Antarctica (EPICA) is a multinational European project for deep ice core drilling in Antarctica. Its main objective is to obtain full documentation of the climatic and atmospheric record archived in Antarctic ice by drilling and analyzing two ice cores and comparing these with their Greenland counterparts (GRIP and GISP). Evaluation of these records will provide information about the natural climate variability and mechanisms of rapid climatic changes during the last glacial epoch.