Santiago de Cali , usually known by its short name "Cali", is the capital of the Valle del Cauca department, and the most populous city in Southwestern Colombia, with an estimated 2,319,655 residents according to 2005-2020/DANE population projections. The city spans with of urban area, making Cali the third largest city proper and metropolitan area in population and the second largest city by area in the country. As the only major Colombian city with access to the Pacific coast, Cali is the main urban and economic centre in Southwestern Colombia, and is one of the fastest growing economies in the country. Cali is also known as the capital of Salsa music. The city was founded on 25 July 1536 by the Spanish conquistador Sebastián de Belalcázar.

Calì, also written in English as Cali, is an Italian surname, widespread mainly in the Ionian side of Sicily. For the surname Calì is assumed the origin of the Greek word kalos (beautiful), or from its Sanskrit root kali, "time."

The Center for Computer-Assisted Legal Instruction, also known as CALI, is a 501(c)(3) non-profit consortium of mostly US law schools that conducts applied research and development in the area of computer-mediated legal education. The organization is best known in law schools for CALI Lessons, online interactive tutorials in legal subjects, and CALI Excellence for the Future Awards (CALI Awards), given to the highest scorer in a law school course at many CALI member law schools. Nearly every US law school is a member of CALI.