Angiogenin (Ang) also known as
ribonuclease 5 is a small 123 amino acid
protein that in humans is encoded by the
ANG gene. Angiogenin is a potent stimulator of new blood vessels through the process of
angiogenesis. Ang hydrolyzes cellular
RNA, resulting in modulated levels of protein synthesis and interacts with
DNA causing a promoter-like increase in the expression of
rRNA. Ang is associated with cancer and neurological disease through
angiogenesis and through activating gene expression that suppresses
apoptosis.
