The Agame (Tigrinya ዓጋመ ʿāgāme, Amharic ዓጋሜ āgāmē, "fruitful") is a former province in northern Ethiopia, now part of the Tigray Region. Its inhabitants include the Irob people, a region where tradition states the legendary Makeda (the Queen of Sheba) was born and raised. The aristocratic house had its capital at Adigrat.

Agamé is an arrondissement in the Mono department of Benin. It is an administrative division under the jurisdiction of the commune of Lokossa. According to the population census conducted by the Institut National de la Statistique Benin on February 15, 2002, the arrondissement had a total population of 11,465.