Actinobacteria is a phylum of
Gram-positive bacteria with high
guanine and cytosine content in their
DNA. The G+C content of Actinobacteria can be as high as 70%, though some may have a low G+C content. They can be
terrestrial or
aquatic. Although understood primarily as soil bacteria, they might be more abundant in freshwaters. Actinobacteria is one of the dominant bacterial phyla and contains one of the largest of bacterial genera,
Streptomyces. Analysis of
glutamine synthetase sequence has been suggested for phylogenetic analysis of Actinobacteria.