The
sarcolemma (
sarco (from sarx) from Greek; flesh, and
lemma from Greek; sheath.) also called the
myolemma, is the
cell membrane of a
striated muscle fiber cell. It consists of a
plasma membrane, which is a
lipid bilayer, and an outer coat consisting of a thin layer of polysaccharide material (
glycocalyx) that contacts the
basement membrane, which contains numerous thin
collagen fibrils and specialized proteins such as
laminin that provide a scaffold for the muscle fiber to adhere to. Through transmembrane proteins residing in the plasma membrane, the actin skeleton inside the cell is connected to the basement membrane and the cell's exterior. At each end of the muscle fiber, the surface layer of the sarcolemma fuses with a tendon fiber, and the tendon fibers in turn collect into bundles to form the muscle tendons that then adhere onto bones.